AFTPH Antibody

Code CSB-PA001422LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA001422LA01HU at dilution of 1:100
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) AFTPH Polyclonal antibody
Uniprot No.
Target Names
AFTPH
Alternative Names
AFTIN_HUMAN antibody; Aftiphilin antibody; Aftiphilin protein antibody; Aftph antibody; MGC33965 antibody; Nbla10388 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Aftiphilin protein (752-889AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The AFTPH Antibody (Product code: CSB-PA001422LA01HU) is Non-conjugated. For AFTPH Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA001422LB01HU AFTPH Antibody, HRP conjugated ELISA
FITC CSB-PA001422LC01HU AFTPH Antibody, FITC conjugated
Biotin CSB-PA001422LD01HU AFTPH Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of clathrin-coated vesicles. Component of the aftiphilin/p200/gamma-synergin complex, which plays roles in AP1G1/AP-1-mediated protein trafficking including the trafficking of transferrin from early to recycling endosomes, and the membrane trafficking of furin and the lysosomal enzyme cathepsin D between the trans-Golgi network (TGN) and endosomes.
Gene References into Functions
  1. the aftiphilin/p200/gamma-synergin complex facilitates AP-1 function PMID: 15758025
  2. Data show that by recruiting aftiphilin/gamma-synergin in addition to clathrin, AP-1 coordinates formation of Weibel-Palade bodies with their acquisition of a regulated secretory phenotype. PMID: 18815278
Subcellular Location
Cytoplasm. Cytoplasm, perinuclear region. Cytoplasmic vesicle, clathrin-coated vesicle.
Database Links

HGNC: 25951

STRING: 9606.ENSP00000238855

UniGene: Hs.655167

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