ASZ1 Antibody

Code CSB-PA002256GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
ASZ1
Alternative Names
ASZ1 antibody; ALP1 antibody; ANKL1 antibody; C7orf7 antibody; GASZAnkyrin repeat antibody; SAM and basic leucine zipper domain-containing protein 1 antibody; Ankyrin-like protein 1 antibody; Germ cell-specific ankyrin antibody; SAM and basic leucine zipper domain-containing protein antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human ASZ1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.
Gene References into Functions
  1. Data reveal a potential role of GASZ during embryonic germ cell development and provide a powerful in vitro system for dissecting the molecular pathways in early germ cell formation during embryogenesis. PMID: 23816659
Subcellular Location
Cytoplasm.
Tissue Specificity
Expressed exclusively in the testis and ovary and at higher levels in the adult testis compared with the adult ovary.
Database Links

HGNC: 1350

OMIM: 605797

KEGG: hsa:136991

STRING: 9606.ENSP00000284629

UniGene: Hs.352412

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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