BCAT2 Antibody

Code CSB-PA002601ESR1HU
Size US$166
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  • Western blot
    All lanes: BCAT2 antibody at 14µg/ml + 293T whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 45, 34 kDa
    Observed band size: 34 kDa

  • Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA002601ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA002601ESR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) BCAT2 Polyclonal antibody
Uniprot No.
Target Names
BCAT2
Alternative Names
BCAM antibody; BCAT 2 antibody; BCAT(m) antibody; BCAT2 antibody; BCAT2_HUMAN antibody; BCATM antibody; BCT2 antibody; Branched chain aminotransferase 2; mitochondrial antibody; Branched-chain-amino-acid aminotransferase antibody; ECA40 antibody; mitochondrial antibody; Placental protein 18 antibody; PP18 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Branched-chain-amino-acid aminotransferase, mitochondrial protein (20-200AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids.
Gene References into Functions
  1. identification of a peroxide-sensitive redox switch at the CXXC motif PMID: 12119021
  2. Studies of ketimine and pyridoxamine phosphate forms of BCAT@ reaction intermediates reveal substrate specificity for L-branched chain amino acids via a group of hydrophobic residues that form three hydrophobic surfaces and lock the side chain in place. PMID: 12269802
  3. role of cysteine residues in the regulatory CXXC motif PMID: 15182179
  4. ption of the CXXC center results in altered substrate orientation and deprotonation of the amino group of pyridoxamine 5'-phosphate, which inhibits catalysis PMID: 17050531
Subcellular Location
[Isoform A]: Mitochondrion.; [Isoform B]: Cytoplasm.
Protein Families
Class-IV pyridoxal-phosphate-dependent aminotransferase family
Tissue Specificity
Ubiquitous.
Database Links

HGNC: 977

OMIM: 113530

KEGG: hsa:587

STRING: 9606.ENSP00000322991

UniGene: Hs.512670

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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