BCKDK Antibody

Code CSB-PA182563
Size US$297
Order now
Image
  • Western blot analysis of extracts from 293 cells and Jurkat cells, using BCKD antibody.
  • Immunofluorescence analysis of HeLa cells, using BCKD antibody.
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) BCKDK Polyclonal antibody
Uniprot No.
Target Names
BCKDK
Alternative Names
[3 methyl 2 oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial antibody; [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase antibody; BCKD kinase antibody; BCKD-kinase antibody; BCKD_HUMAN antibody; BCKDHKIN antibody; Bckdk antibody; BCKDKD antibody; BDK antibody; Branched chain alpha keto acid dehydrogenase kinase antibody; Branched chain ketoacid dehydrogenase kinase antibody; Branched-chain alpha-ketoacid dehydrogenase kinase antibody; mitochondrial antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from Internal of Human BCKD.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB,IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
IF 1:100-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex.
Gene References into Functions
  1. our study indicates that BCKDK promotes colorectal tumorigenesis through up-regulation of the MAPK signaling pathway by phosphorylating MEK at Ser221. PMID: 28501528
  2. There is a relationship between plamsa CST and BCKDK in sepsis patients. PMID: 27773658
  3. Results demonstrate that BCKDK mutations can result in neurobehavioral deficits in humans. PMID: 24449431
  4. This publication is about the mouse gene but contains the 5' sequence of the human gene, including upstream open reading frame information. PMID: 15302860
  5. employment of multidimensional heteronuclear NMR techniques to determine the structure and dynamics of the LBD of the human branched-chain alpha-keto acid dehydrogenase complex (hbLBD) PMID: 11839747

Show More

Hide All

Involvement in disease
Branched-chain ketoacid dehydrogenase kinase deficiency (BCKDKD)
Subcellular Location
Mitochondrion matrix. Mitochondrion.
Protein Families
PDK/BCKDK protein kinase family
Tissue Specificity
Ubiquitous.
Database Links

HGNC: 16902

OMIM: 614901

KEGG: hsa:10295

STRING: 9606.ENSP00000219794

UniGene: Hs.513520

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*