CCT4 Antibody

Code CSB-PA004859GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
CCT4
Alternative Names
CCT4 antibody; CCTD antibody; SRB antibody; T-complex protein 1 subunit delta antibody; TCP-1-delta antibody; CCT-delta antibody; Stimulator of TAR RNA-binding antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human CCT4
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin.
Gene References into Functions
  1. Chaperonin CCT is required for the correct folding of eIF3h and eIF3i subunits. PMID: 24320561
  2. Both CCT4 and CCT5 homo-oligomers have the property of forming 8-fold double rings absent the other subunits, and these complexes carry out chaperonin reactions without other partner subunits. PMID: 23612981
Subcellular Location
Cytoplasm. Melanosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body.
Protein Families
TCP-1 chaperonin family
Database Links

HGNC: 1617

OMIM: 605142

KEGG: hsa:10575

STRING: 9606.ENSP00000377958

UniGene: Hs.421509

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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