CDK5R2 Antibody

Datasheet

Code	CSB-PA003663
Size	US$119
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Image	Western Blot analysis of HuvEc cells using p39 Polyclonal Antibody
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q13319

Target Names

CDK5R2

Alternative Names

CD5R2_HUMAN antibody; CDK5 activator 2 antibody; Cdk5r2 antibody; Cyclin dependent kinase 5 activator 2 antibody; Cyclin dependent kinase 5 activator isoform p39i antibody; Cyclin dependent kinase 5 regulatory subunit 2 antibody; Cyclin-dependent kinase 5 activator 2 antibody; Cyclin-dependent kinase 5 regulatory subunit 2 antibody; NCK5AI antibody; Neuronal CDK5 activator isoform antibody; p39 antibody; P39I antibody; p39nck5ai antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthesized peptide derived from the Internal region of Human p39.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB, IHC, ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:100-1:300
ELISA	1:20000

Protocols

Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Activator of CDK5/TPKII.

Gene References into Functions

p39 is essential for recruiting scaffolding protein muskelin to stress fibers. PMID: 25128817
Hepatocellular carcinoma patients with lower p39 expression had poorer overall survival rate than that with high expression. PMID: 20936377
Our data suggest that neurotoxic insults lead to calpain-mediated conversion of p39 to p29, which might contribute to deregulation of Cdk5 PMID: 11784720
role of the CDK5 molecular complex in the genetic etiology of early-onset Alzheimer disease; a yet unknown functional variant in CDK5 or in a nearby gene might lead to increased susceptibility for early-onset Alzheimer disease PMID: 15917097

Subcellular Location

Cell membrane; Lipid-anchor; Cytoplasmic side.

Protein Families

Cyclin-dependent kinase 5 activator family

Tissue Specificity

Brain and neuron specific.

Database Links

HGNC: 1776

OMIM: 603764

KEGG: hsa:8941

STRING: 9606.ENSP00000304250

UniGene: Hs.158460

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Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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