CES3 Antibody

Datasheet

Code	CSB-PA005260LA01HU
Size	US$166
	Order now
Image	Immunohistochemistry of paraffin-embedded human appendix tissue using CSB-PA005260LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA005260LA01HU at dilution of 1:100 Immunofluorescent analysis of Hela cells using CSB-PA005260LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Promotion
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CES3 Polyclonal antibody

Uniprot No.

Q6UWW8

Target Names

CES3

Alternative Names

Carboxylesterase 3 antibody; CES 3 antibody; Ces3 antibody; ES3 antibody; EST3_HUMAN antibody; FLJ21736 antibody; Liver carboxylesterase 31 homolog antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Carboxylesterase 3 protein (65-233AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The CES3 Antibody (Product code: CSB-PA005260LA01HU) is Non-conjugated. For CES3 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA005260LB01HU	CES3 Antibody, HRP conjugated	ELISA
FITC	CSB-PA005260LC01HU	CES3 Antibody, FITC conjugated
Biotin	CSB-PA005260LD01HU	CES3 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function

Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows low catalytic efficiency for hydrolysis of CPT-11 (7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin), a prodrug for camptothecin used in cancer therapeutics.

Gene References into Functions

This study provides the first evidence of functional compensation whereby increased expression of CES3 restores intracellular cholesteryl ester hydrolytic activity and free cholesterol efflux in CES1-deficient cells. PMID: 22700792
Studies indicate that CES3 mRNA isoform expression in several tissues, particularly in colon, trachea and in brain. PMID: 20422440
CES3 seems to have a lower catalytic efficiency than the other two CESs for selected substrates. PMID: 19508181
pharmacogenomic characterization of human carboxylesterase 1A1, 1A2, and 1A3 genes PMID: 18794728

Subcellular Location

Endoplasmic reticulum lumen.

Protein Families

Type-B carboxylesterase/lipase family

Tissue Specificity

Expressed in liver, colon and small intestine.

Database Links

HGNC: 1865

OMIM: 605279

KEGG: hsa:23491

STRING: 9606.ENSP00000304782

UniGene: Hs.268700

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

Join us with

Subscribe newsletter

Leave a message

Message

Product >> Product Name：
Product >> Code：
Name： *
Email： *
Company/Organization：
Phone：
Since emails may get flagged by spam filters occasionally, we recommend leaving your phone number as a precaution. Your information is safe with us.
Question/Comment： *
Your Region： *
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
CAPTCHA verification：
If CAPTCHA verification fails, click to refresh the CAPTCHA and try again.

Place an order now

I. Product details

Product name *

Code *

Size *

Quantity *

Message

II. Contact details

Name *

Email address *

Company/Organization

Phone

III. Ship To

Address *

City *

State/Province *

Zip/Post code *

Country *

Attn Name *

Phone# *

IV. Bill To Same as Shipping Address