CLPS Antibody

Datasheet

Code	CSB-PA469305
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA469305(CLPS Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA469305(CLPS Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200)
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

P04118

Target Names

CLPS

Alternative Names

clpS antibody; COL_HUMAN antibody; Colipase antibody; Colipase pancreatic antibody; Pancreatic colipase preproprotein antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Fusion protein of Human CLPS

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:2000-1:5000
IHC	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.; Enterostatin has a biological activity as a satiety signal.

Gene References into Functions

Low CLPS expression is associated with pancreatic cancer. PMID: 23918603
humans with the Arg92Cys substitution will secrete less functional colipase PMID: 23204298
found no evidence for an association of pancreatic colipase(CLPS) single nucleotide polymorphisms rs2766597, rs41270082, rs3748050, and rs3748051 with obesity or percentage of dietary fat intake PMID: 20054203
evidence in two German Caucasian study populations that the variant of the rare colipase Arg109Cys polymorphism might contribute to increased susceptibility of type 2 diabetes PMID: 16189801
Our findings demonstrate that the Arg92Cys polymorphism decreases the function of Cys92 colipase. This change may contribute to the development of type 2 diabetes. PMID: 17715423
CLPS genetic variability associates with insulin secretory function in non-diabetic humans and may represent a novel candidate gene for development of type 2 diabetes PMID: 18726866

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Subcellular Location

Secreted.

Protein Families

Colipase family

Tissue Specificity

Expressed by the pancreas.

Database Links

HGNC: 2085

OMIM: 120105

KEGG: hsa:1208

STRING: 9606.ENSP00000259938

UniGene: Hs.1340

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Phage Display Service

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Protein Service

Gene Synthesis Service

Oligo Synthesis Service

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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