CLPS Antibody

Code CSB-PA005578GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
CLPS
Alternative Names
clpS antibody; COL_HUMAN antibody; Colipase antibody; Colipase pancreatic antibody; Pancreatic colipase preproprotein antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human CLPS
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.; Enterostatin has a biological activity as a satiety signal.
Gene References into Functions
  1. Low CLPS expression is associated with pancreatic cancer. PMID: 23918603
  2. humans with the Arg92Cys substitution will secrete less functional colipase PMID: 23204298
  3. found no evidence for an association of pancreatic colipase(CLPS) single nucleotide polymorphisms rs2766597, rs41270082, rs3748050, and rs3748051 with obesity or percentage of dietary fat intake PMID: 20054203
  4. evidence in two German Caucasian study populations that the variant of the rare colipase Arg109Cys polymorphism might contribute to increased susceptibility of type 2 diabetes PMID: 16189801
  5. Our findings demonstrate that the Arg92Cys polymorphism decreases the function of Cys92 colipase. This change may contribute to the development of type 2 diabetes. PMID: 17715423
  6. CLPS genetic variability associates with insulin secretory function in non-diabetic humans and may represent a novel candidate gene for development of type 2 diabetes PMID: 18726866

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Subcellular Location
Secreted.
Protein Families
Colipase family
Tissue Specificity
Expressed by the pancreas.
Database Links

HGNC: 2085

OMIM: 120105

KEGG: hsa:1208

STRING: 9606.ENSP00000259938

UniGene: Hs.1340

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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