CMTM3 Antibody

1. CMTM3 exhibited a lower expression pattern in gastric cancer tissues.MiR-135b-5p promotes gastric cancer progression by targeting CMTM3. PMID: 29345297
2. this study demonstrates that knockdown of CMTM3 promotes the metastasis of gastric cancer through the STAT3/Twist1/EMT pathway PMID: 27121055
3. CMTM3 was significantly hypermethylated in colorectal cancer tissues when compared with adjacent normal colorectal tissues. PMID: 28782576
4. CMTM3 decreases EGFR expression, facilitates EGFR degradation, and inhibits the EGF-mediated tumorigenicity of gastric cancer cells by enhancing Rab5 activity. PMID: 27867015
5. CMTM3 mediates cell-cell adhesion at adherens junctions and contributes to the control of vascular sprouting by regulation VE-cadherin turnover. PMID: 28428220
6. Overexpression of CMTM3 attenuated the tumor growth of hepatocellular carcinoma. PMID: 27629543
7. identified CMTM3 as a novel secretory protein released via exosomes in the prostate PMID: 27125975
8. study indicates that elevated CMTM3 methylation is a risk factor in male LSCC patients, especially in the patients with age over 55years and with smoking behavior PMID: 27521994
9. Reduced expression of CMTM3 is associated with prostate cancer. PMID: 25990505
10. Low expression of CMTM3 was associated with metastasis and recurrence of oral squamous cell carcinoma. PMID: 25946973
11. CMTM3 is significantly down-regulated in clear cell renal cell carcinoma and exerts remarkable tumor-suppressive functions PMID: 23907292
12. Peritoneal disseminated metastases were significantly suppressed by CMTM3. PMID: 24131472
13. CMTM3/CKLFSF3 is an evolutionarily conserved gene that may have important roles in the male reproductive system and immune system. PMID: 17002874
14. CMTM3 inhibits prostate-specific antigen expression at both mRNA and protein levels with no obvious influence on androgen receptor expression. PMID: 18402773

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HGNC: 19174

OMIM: 607886

KEGG: hsa:123920

STRING: 9606.ENSP00000354579

UniGene: Hs.298198