COQ5 Antibody

Code CSB-PA005804GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
COQ5
Alternative Names
COQ52-methoxy-6-polyprenyl-1,4-benzoquinol methylase antibody; mitochondrial antibody; EC 2.1.1.201 antibody; Ubiquinone biosynthesis methyltransferase COQ5 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human COQ5
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
Gene References into Functions
  1. This is the first report of primary CoQ10 deficiency caused by loss of function of COQ5, with delineation of the clinical, laboratory, histological, and molecular features, and insights regarding targeted treatment with CoQ10 supplementation. PMID: 29044765
  2. The expression of COQ5 was increased. PMID: 27155576
  3. The results that knockdown of the COQ5 gene reduced CoQ10 levels further indicated the critical role of COQ5 in the biosynthesis of CoQ10. PMID: 23354120
Subcellular Location
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein Families
Class I-like SAM-binding methyltransferase superfamily, MenG/UbiE family
Tissue Specificity
Widely expressed, with highest levels in liver, lung, placenta and skeletal muscle.
Database Links

HGNC: 28722

OMIM: 616359

KEGG: hsa:84274

STRING: 9606.ENSP00000288532

UniGene: Hs.17250

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