CYB5R2 Antibody

Code CSB-PA738178LA01HU
Size US$166
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  • Western blot
    All lanes: CYB5R2 antibody at 4µg/ml + Mouse kidney tissue
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 32, 28 kDa
    Observed band size: 32 kDa

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA738178LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CYB5R2 Polyclonal antibody
Uniprot No.
Target Names
CYB5R2
Alternative Names
b5R.2 antibody; Cyb5r2 antibody; Cytochrome b5 reductase 2 antibody; Cytochrome b5 reductase b5R.2 antibody; NADH cytochrome b5 reductase 2 antibody; NADH-cytochrome b5 reductase 2 antibody; NB5R2_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human NADH-cytochrome b5 reductase 2 protein (1-237AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The CYB5R2 Antibody (Product code: CSB-PA738178LA01HU) is Non-conjugated. For CYB5R2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA738178LB01HU CYB5R2 Antibody, HRP conjugated ELISA
FITC CSB-PA738178LC01HU CYB5R2 Antibody, FITC conjugated
Biotin CSB-PA738178LD01HU CYB5R2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction. Responsible for NADH-dependent lucigenin chemiluminescence in spermatozoa by reducing both lucigenin and 2-[4-iodophenyl]-3-[4-nitrophenyl]-5-[2,4-disulfophenyl]-2H tetrazolium monosodium salt (WST-1).
Gene References into Functions
  1. Study showed that multifocal or multicentric glioblastomas have some underlying genetic and epigenetic characteristics that are associated with poor prognosis and that CYB5R2 is a new epigenetic marker for glioblastoma prognosis PMID: 26323991
  2. findings suggest that CYB5R2 may be a functional tumor suppressor gene, frequently inactivated by hypermethylation of its promoter in nasopharyngeal carcinoma PMID: 24338690
  3. CYB5R2 is a key enzyme involved in the mediation of NADH-induced redox activity in human spermatozoa. PMID: 15858218
Protein Families
Flavoprotein pyridine nucleotide cytochrome reductase family
Tissue Specificity
Restricted expression.
Database Links

HGNC: 24376

OMIM: 608342

KEGG: hsa:51700

STRING: 9606.ENSP00000299498

UniGene: Hs.414362

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