DDX24 Antibody

Code CSB-PA040035
Size US$100
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Product Details

Uniprot No.
Target Names
DDX24
Alternative Names
ATP dependent RNA helicase DDX24 antibody; ATP-dependent RNA helicase ddx24 antibody; DDX 24 antibody; ddx24 antibody; DDX24_HUMAN antibody; DEAD (Asp Glu Ala Asp) box polypeptide 24 antibody; DEAD box protein 24 antibody; DEAD/H (Asp Glu Ala Asp) box polypeptide 24 antibody; S. cerevisiae CHL1 like helicase antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the N-terminal region of Human DDX24.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
IHC, ELISA
Recommended Dilution
Application Recommended Dilution
IHC 1:100-1:300
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
ATP-dependent RNA helicase.
Gene References into Functions
  1. DDX24 is a negative regulator of p53 transcriptional activity.DDX24 inhibits p300 mediated acetylation of p53. PMID: 25867071
  2. depletion of DDX24 in cells impaired pre-rRNA processing and resulted both in abrogation of MDM2 function and in consequent p53 stabilization PMID: 24980433
  3. knockdown of a DEAD-box protein named DDX24 inhibits the packaging of HIV-1 RNA and thus diminishes viral infectivity. PMID: 18289627
Protein Families
DEAD box helicase family, DDX24/MAK5 subfamily
Tissue Specificity
Ubiquitous. Most abundant in heart and brain, but with lowest levels in thymus and small intestine.
Database Links

HGNC: 13266

OMIM: 606181

KEGG: hsa:57062

STRING: 9606.ENSP00000328690

UniGene: Hs.510328

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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