DHX8 Antibody

Code CSB-PA596171
Size US$297
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  • Western blot analysis of extracts from HeLa cells, Jurkat cells and HepG2 cells, using DHX8 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) DHX8 Polyclonal antibody
Uniprot No.
Target Names
DHX8
Alternative Names
ATP dependent RNA helicase DHX8 antibody; ATP-dependent RNA helicase dhx8 antibody; DDX 8 antibody; DDX8 antibody; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 8 (RNA helicase) antibody; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 8 antibody; DEAD/H box 8 antibody; DEAD/H box polypeptide 8 antibody; DEAH (Asp Glu Ala His) box polypeptide 8 antibody; DEAH box polypeptide 8 antibody; DEAH box protein 8 antibody; DHX 8 antibody; dhx8 antibody; DHX8_HUMAN antibody; HRH 1 antibody; HRH1 antibody; PRP 22 antibody; PRP22 antibody; PRP22; S. cerevisiae; homolog of antibody; PRPF 22 antibody; PRPF22 antibody; RNA helicase HRH 1 antibody; RNA helicase HRH1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from internal of Human DHX8.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in pre-mRNA splicing as component of the spliceosome. Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome.
Gene References into Functions
  1. cellular complexes comprising cactin, DHX8 and SRRM2 sustain precise chromosome segregation, genome stability and cell proliferation by allowing faithful splicing of specific pre-mRNAs. PMID: 28062851
  2. structural and functional analysis of C-terminal domain of the spliceosomal helicase Prp22 PMID: 23096351
  3. Preliminary X-ray diffraction analysis of the crystals of the C-terminal domain of the human DExD/H-box protein hPrp22 at 2.1 A resolution, is reported. PMID: 19724143
Subcellular Location
Nucleus.
Protein Families
DEAD box helicase family, DEAH subfamily, DDX8/PRP22 sub-subfamily
Tissue Specificity
Expressed in skin, cervix and nerve. Also expressed in the brain.
Database Links

HGNC: 2749

OMIM: 600396

KEGG: hsa:1659

STRING: 9606.ENSP00000262415

UniGene: Hs.463105

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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