DHX8 Antibody

Datasheet

Code	CSB-PA002114
Size	US$119
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Image	Western Blot analysis of HepG2 cells using DDX8 Polyclonal Antibody
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q14562

Target Names

DHX8

Alternative Names

ATP dependent RNA helicase DHX8 antibody; ATP-dependent RNA helicase dhx8 antibody; DDX 8 antibody; DDX8 antibody; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 8 (RNA helicase) antibody; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 8 antibody; DEAD/H box 8 antibody; DEAD/H box polypeptide 8 antibody; DEAH (Asp Glu Ala His) box polypeptide 8 antibody; DEAH box polypeptide 8 antibody; DEAH box protein 8 antibody; DHX 8 antibody; dhx8 antibody; DHX8_HUMAN antibody; HRH 1 antibody; HRH1 antibody; PRP 22 antibody; PRP22 antibody; PRP22; S. cerevisiae; homolog of antibody; PRPF 22 antibody; PRPF22 antibody; RNA helicase HRH 1 antibody; RNA helicase HRH1 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthesized peptide derived from the Internal region of Human DDX8.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB, ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:5000

Protocols

Western Blotting(WB) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Involved in pre-mRNA splicing as component of the spliceosome. Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome.

Gene References into Functions

cellular complexes comprising cactin, DHX8 and SRRM2 sustain precise chromosome segregation, genome stability and cell proliferation by allowing faithful splicing of specific pre-mRNAs. PMID: 28062851
structural and functional analysis of C-terminal domain of the spliceosomal helicase Prp22 PMID: 23096351
Preliminary X-ray diffraction analysis of the crystals of the C-terminal domain of the human DExD/H-box protein hPrp22 at 2.1 A resolution, is reported. PMID: 19724143

Subcellular Location

Nucleus.

Protein Families

DEAD box helicase family, DEAH subfamily, DDX8/PRP22 sub-subfamily

Tissue Specificity

Expressed in skin, cervix and nerve. Also expressed in the brain.

Database Links

HGNC: 2749

OMIM: 600396

KEGG: hsa:1659

STRING: 9606.ENSP00000262415

UniGene: Hs.463105

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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