DLGAP1 Antibody

Datasheet

Code	CSB-PA004048
Size	US$100
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Image	Western Blot analysis of 293 cells using SAPAP1 Polyclonal Antibody
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

O14490

Target Names

DLGAP1

Alternative Names

4933422O14Rik antibody; 9630002F18 antibody; AI845682 antibody; AI848168 antibody; BB075781 antibody; D17Bwg0511e antibody; DAP 1 ALPHA antibody; DAP 1 antibody; DAP 1 BETA antibody; DAP-1 antibody; DAP-1-ALPHA antibody; DAP-1-BETA antibody; DAP1 antibody; Discs large (Drosophila) homolog associated protein 1 antibody; Discs large homolog associated protein 1 antibody; Disks large associated protein 1 antibody; Disks large associated protein 1; alpha isoform; included antibody; Disks large associated protein 1; beta isoform; included antibody; Disks large-associated protein 1 antibody; DLGAP 1 antibody; Dlgap1 antibody; DLGP1_HUMAN antibody; GKAP antibody; GKAP/SAPAP antibody; GKPA/SAPAP antibody; Guanylate kinase associated protein antibody; Guanylate kinase-associated protein antibody; hGKAP antibody; KIAA4162 antibody; MGC88156 antibody; mKIAA4162 antibody; PSD 95/SAP90 binding protein 1 antibody; PSD-95/SAP90-binding protein 1 antibody; SAP90/PSD 95 associated protein 1 antibody; SAP90/PSD-95-associated protein 1 antibody; SAPAP 1 antibody; SAPAP1 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthesized peptide derived from the C-terminal region of Human SAPAP1.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB, IHC, IF, ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:100-1:300
IF	1:200-1:1000
ELISA	1:40000

Protocols

Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Part of the postsynaptic scaffold in neuronal cells.

Gene References into Functions

This study revealed a significant variant (rs12455524) within the gene DLGAP1 for Recurrent major depression. PMID: 26485182
These results strongly suggested involvement of the DLGAP1 gene product in the development of HIV-related lipoatrophy in Thai HIV patients. PMID: 25950743
This study showed that DLGAP1 association with obsessive-compulsive disorder. PMID: 24821223
Dimerization of DLC2 was required for its interaction with GKAP, which, in turn, potentiated GKAP self-association. PMID: 24938595
Results show that the expression and distribution of NMDA receptors subunits GluN1, GluN2A and GluN2B - together with that of postsynaptic protein PSD-95 - are modified in Alzheimer's disease compared to normal aging PMID: 24156266
dlgap1 showed the highest association, of snps examined, with ocd. PMID: 22889921
Study identified six genetic variants, (rs145691437, rs3786431, rs201567254, rs3745051 and rs11662259) and one rare missense mutation (c.1922A>G). SNP- and haplotype-based analyses showed no association of these SNPs with schizophrenia. PMID: 22940546
The GKAP controls the forces operating on microtubules and play a fundamental role in centrosome positioning and cell polarity. PMID: 21041448

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Subcellular Location

Cell membrane; Peripheral membrane protein. Cell junction, synapse, postsynaptic density. Cell junction, synapse.

Protein Families

SAPAP family

Tissue Specificity

Expressed in brain.

Database Links

HGNC: 2905

OMIM: 605445

KEGG: hsa:9229

STRING: 9606.ENSP00000316377

UniGene: Hs.594640

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Glutamatergic synapse

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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