EEF1D Antibody

Code CSB-PA007431LA01HU
Size US$166
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Image
  • Western blot
    All lanes: EEF1D antibody at 2µg/ml + MCF-7 whole cell lysate
    Secondary
    Goat polyclonal to rabbit lgG at 1/15000 dilution
    Predicted band size: 32, 72, 29, 30 kDa
    Observed band size: 32 kDa
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) EEF1D Polyclonal antibody
Uniprot No.
Target Names
EEF1D
Alternative Names
Antigen NY CO 4 antibody; Antigen NY-CO-4 antibody; EEF 1D antibody; EEF1D antibody; EF 1 delta antibody; EF 1D antibody; EF-1-delta antibody; EF1D antibody; EF1D_HUMAN antibody; Elongation factor 1 delta antibody; Elongation factor 1-delta antibody; eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) antibody; Eukaryotic translation elongation factor 1 delta antibody; FP1047 antibody; Guanine nucleotide exchange protein antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Elongation factor 1-delta protein (2-281AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The EEF1D Antibody (Product code: CSB-PA007431LA01HU) is Non-conjugated. For EEF1D Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA007431LB01HU EEF1D Antibody, HRP conjugated ELISA
FITC CSB-PA007431LC01HU EEF1D Antibody, FITC conjugated
Biotin CSB-PA007431LD01HU EEF1D Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome.; Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE).
Gene References into Functions
  1. eukaryotic translation elongation factor 1delta knockdown in oral squamous cell carcinoma reduced cell proliferation and induced EMT (epithelial-mesenchymal transition) phenotypes PMID: 26823560
  2. Taken together, our data suggest EFF1D functions as a novel negative regulator of SIAH-1 PMID: 21633900
  3. overexpression is positively correlated with malignant transformation of 16HBE cells induced by CdC12, but is not correlated with DNA mutations PMID: 20514991
  4. These results further confirm that overexpression of TEF-1 delta is oncogenic and the antisense TEF-1 delta mRNA expression reverses its oncogenic potential. PMID: 12210501
  5. Interaction between HrHRF and EF-1delta taken with some of the recently published information concerning the TCTP (HrHRF) mentioned above suggest a possible intracellular role for TCTP/HrHRF. PMID: 15062873
  6. Increased EF-1 delta mRNA expression is associated with lymph node metastases and advanced disease stages in esophageal carcinoma PMID: 15199388
  7. Gain of 8q-mapped EF-1 delta is associated with adverse outcome in Medulloblastoma. PMID: 16968546
  8. Repression of deltaEF1 plays a key role in mediating BMP-6-induced transcriptional activation of E-cadherin in breast cancer cells. PMID: 17997862

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Subcellular Location
[Isoform 2]: Nucleus.
Protein Families
EF-1-beta/EF-1-delta family
Tissue Specificity
Isoform 2 is specifically expressed in brain, cerebellum and testis.
Database Links

HGNC: 3211

OMIM: 130592

KEGG: hsa:1936

STRING: 9606.ENSP00000391944

UniGene: Hs.333388

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