EIF2D Antibody

Code CSB-PA012909GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
EIF2D
Alternative Names
Eukaryotic translation initiation factor 2D antibody; HCA56 antibody; Hepatocellular carcinoma associated antigen 56 antibody; Hepatocellular carcinoma-associated antigen 56 antibody; LGTN antibody; LIGA_HUMAN antibody; Ligatin antibody; OTTHUMP00000034537 antibody; OTTHUMP00000034538 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human LGTN
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Translation initiation factor that is able to deliver tRNA to the P-site of the eukaryotic ribosome in a GTP-independent manner. The binding of Met-tRNA(I) occurs after the AUG codon finds its position in the P-site of 40S ribosomes, the situation that takes place during initiation complex formation on some specific RNAs. Its activity in tRNA binding with 40S subunits does not require the presence of the aminoacyl moiety. Possesses the unique ability to deliver non-Met (elongator) tRNAs into the P-site of the 40S subunit. In addition to its role in initiation, can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits.
Gene References into Functions
  1. Data suggest that neither eIF2A nor eIF2D are involved in the translation of this Sindbis virus subgenomic mRNA (sgmRNA) bearing non-AUG codons PMID: 28240315
  2. Reinitiation complexes involving initiation factors eIF2D, MCT-1, and DENR controls the translation of a large fraction of mammalian cellular mRNAs. PMID: 28732596
Subcellular Location
Cytoplasm.
Protein Families
EIF2D family
Database Links

HGNC: 6583

OMIM: 613709

KEGG: hsa:1939

STRING: 9606.ENSP00000271764

UniGene: Hs.497581

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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