EVA1A Antibody

Code CSB-PA862042ESR2HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA862042ESR2HU at dilution of 1:100

  • Immunofluorescent analysis of MCF-7 cells using CSB-PA862042ESR2HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) EVA1A Polyclonal antibody
Uniprot No.
Target Names
EVA1A
Alternative Names
EVA1A; FAM176A; TMEM166; SP24; Protein eva-1 homolog A; Protein FAM176A; Transmembrane protein 166
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protein eva-1 homolog A protein (58-152AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis.
Gene References into Functions
  1. Low EVA1A expression is associated with glioblastoma. PMID: 28185834
  2. The adenovirus-mediated increase of FAM176A inhibited the growth of the tumor cells. PMID: 24257118
  3. TMEM166 expression was widely down-regulated in the cancer tissues. PMID: 22495369
  4. Low TMEM166 mRNA and protein expression is associated with esophageal squamous cell carcinoma. PMID: 23098460
  5. TMEM166 is a novel regulator involved in both autophagy and apoptosis. PMID: 17492404

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Subcellular Location
Endoplasmic reticulum membrane; Single-pass membrane protein. Lysosome membrane; Single-pass membrane protein.
Protein Families
EVA1 family
Tissue Specificity
Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle.
Database Links

HGNC: 25816

KEGG: hsa:84141

STRING: 9606.ENSP00000233712

UniGene: Hs.302346

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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