FAM129B (Ab-712) Antibody

Code CSB-PA998601
Size US$297
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  • Western blot analysis of extracts from 3T3 and DU145 cells using Niban-like protein(Ab-712) antibody.
  • Immunofluorescence staining of methanol-fixed Hela cells using Niban-like protein(Ab-712) antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) FAM129B Polyclonal antibody
Uniprot No.
Target Names
FAM129B
Alternative Names
bA356B19.6 antibody; C9orf88 antibody; chromosome 9 open reading frame 88 antibody; DKFZP434H0820 antibody; FAM129B antibody; family with sequence similarity 129; member B antibody; FLJ13518 antibody; FLJ22151 antibody; FLJ22298 antibody; hypothetical protein LOC64855 antibody; Meg 3 antibody; Meg-3 antibody; Meg3 antibody; Niban like protein 1 antibody; Niban-like protein 1 antibody; NIBL1_HUMAN antibody; OC58 antibody; OTTHUMP00000022187 antibody; OTTHUMP00000022188 antibody; Protein FAM129B antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Peptide sequence around aa.710~714 (Q-V-S-S-P) derived from Human Niban-like protein.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB,IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:1000
IF 1:100-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May play a role in apoptosis suppression. May promote melanoma cell invasion in vitro.
Gene References into Functions
  1. activated EGFR phosphorylates the Y593 residue of the protein known as family with sequence similarity 129, member B (FAM129B), which is overexpressed in many types of human cancer. PMID: 26721396
  2. The rapid induction of apoptosis in FAM129B knockdown cells was reversed by co-transfection with recombinant FAM129B, indicating that its effect on apoptosis was specific. PMID: 21148485
  3. Phosphorylation of FAM129B has a role in controlling melanoma cell invasion. PMID: 19362540
Subcellular Location
Cytoplasm, cytosol. Cell junction, adherens junction. Membrane; Lipid-anchor. Note=In exponentially growing cells, exclusively cytoplasmic. Cell membrane localization is observed when cells reach confluency and during telophase. In melanoma cells, targeting to the plasma membrane may be impaired by C-terminal phosphorylation.
Protein Families
Niban family
Database Links

HGNC: 25282

OMIM: 614045

KEGG: hsa:64855

STRING: 9606.ENSP00000362409

UniGene: Hs.522401

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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