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FAM35AFAM35/B Antibody

Datasheet
Code CSB-PA597588
Size US$297
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  • Western blot analysis of extracts from Jurkat cells, using FAM35A/B antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) FAM35A Polyclonal antibody
Uniprot No.
Q86V20
Target Names
FAM35A
Alternative Names
SHLD2 antibody; FAM35A antibody; RINN2 antibody; Shieldin complex subunit 2 antibody; Protein FAM35A antibody; RINN1-REV7-interacting novel NHEJ regulator 2 antibody; Shield complex subunit 2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from internal of Human FAM35A/B.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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FAM35A Proteins

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Target Background

Function
Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs). During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection. Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres.
Gene References into Functions
  1. the FAM35A locus showed an association with all gout by meta-analysis among the Japanese, Caucasian and NZ Polynesian sample sets at a genome-wide level of significance. PMID: 27899376
Subcellular Location
Nucleus. Chromosome.
Protein Families
FAM35 family
Database Links

HGNC: 28773

KEGG: hsa:54537

UniGene: Hs.500419

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