FOXL1 Antibody

Datasheet

Code	CSB-PA002568
Size	US$100
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Image	Western Blot analysis of A549 cells using FoxL1 Polyclonal Antibody
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Product Details
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Target Background

Product Details

Uniprot No.

Q12952

Target Names

FOXL1

Alternative Names

FKH 6 antibody; FKH6 antibody; FKHL 11 antibody; FKHL11 antibody; Forkhead (Drosophila) like 11 antibody; Forkhead box L1 antibody; Forkhead box protein L1 antibody; Forkhead related protein FKHL11 antibody; Forkhead related transcription factor 7 antibody; Forkhead-related protein FKHL11 antibody; Forkhead-related transcription factor 7 antibody; FOX L1 antibody; FOXL 1 antibody; Foxl1 antibody; FOXL1_HUMAN antibody; FREAC 7 antibody; FREAC-7 antibody; FREAC7 antibody

Raised in

Rabbit

Species Reactivity

Human,Monkey

Immunogen

Synthesized peptide derived from the Internal region of Human FoxL1.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB, IHC, ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:100-1:300
ELISA	1:20000

Protocols

Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Transcription factor required for proper proliferation and differentiation in the gastrointestinal epithelium. Target gene of the hedgehog (Hh) signaling pathway via GLI2 AND GLI3 transcription factors.

Gene References into Functions

FOXL1 inhibited the proliferation, invasion, and migration of breast cancer.FOXL1 expression was reduced in breast cancer. PMID: 27938507
our findings provide evidence that FOXL1 might serve as a candidate tumor suppressor and a potential prognostic biomarker for gastric cancer PMID: 26960689
the downregulation of FOXL1 expression was associated with osteosarcoma cell growth. Restoration of FOXL1 gene expression by gene therapy may have a therapeutic potential for patients with osteosarcoma PMID: 26062977
dysregulated FOXL1 is involved in tumorigenesis and progression of gallbladder cancer. PMID: 25010679
results suggest that Foxl1 plays an inhibitory role in renal tumor progression. PMID: 24427331
Lower FOXL1 expression is correlated with metastasis and advanced pathologic stage of pancreatic cancer. PMID: 23801748
two novel de novo mutations in rare patients inherited gene variants in FOXL1. PMID: 21457232
FUS-CREB3L2/L1-positive sarcomas show a specific gene expression profile with upregulation of CD24 and FOXL1. PMID: 21536545

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Subcellular Location

Nucleus.

Database Links

HGNC: 3817

OMIM: 603252

KEGG: hsa:2300

STRING: 9606.ENSP00000326272

UniGene: Hs.533830

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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