GADL1 Antibody

Code CSB-PA009166GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
GADL1
Alternative Names
GADL1Acidic amino acid decarboxylase GADL1 antibody; Aspartate 1-decarboxylase antibody; ADC antibody; HuADC antibody; EC 4.1.1.11 antibody; Cysteine sulfinic acid decarboxylase antibody; CSADC antibody; HuCSADC antibody; EC 4.1.1.29 antibody; Glutamate decarboxylase-like protein 1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human GADL1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May catalyze the decarboxylation of L-aspartate, 3-sulfino-L-alanine (cysteine sulfinic acid), and L-cysteate to beta-alanine, hypotaurine and taurine, respectively. Does not exhibit any decarboxylation activity toward glutamate.
Gene References into Functions
  1. No difference in GADL1 expression was observed among lymphoblastoid cells from excellent-responders, non-responders or controls. Furthermore, lithium did not induce significant changes in GADL1 expression levels after 4 or 8 days. These results did not support an association of GADL1 expression in the determination of a lithium response in BD patients. PMID: 28214779
  2. taurine biosynthesis in vertebrates involves two structurally related PLP-dependent decarboxylases (cysteine sulfinic acid decarboxylase and glutamic acid decarboxylase like 1) PMID: 26327310
  3. The study did not identify a major relationship between the GADL1 polymorphisms and lithium response in an Indian population. PMID: 25415457
  4. Genetic variations in GADL1 are associated with the response to lithium maintenance treatment for bipolar I disorder in patients of Han Chinese descent. PMID: 24369049
Protein Families
Group II decarboxylase family
Tissue Specificity
Expressed very weakly in neurons and not detected in astrocytes, brain or liver.
Database Links

HGNC: 27949

OMIM: 615601

KEGG: hsa:339896

STRING: 9606.ENSP00000282538

UniGene: Hs.657052

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