GAS7 Antibody

1. Polymorphism rs11656696 is not associated with primary open angle glaucoma (POAG) nor any of its endophenotypic traits such as intraocular pressure and cup/disk ratio and is thus not a risk factor for POAG in this Saudi cohort PMID: 29022762
2. Collectively, our findings provide a novel basis for using miR-181a/GAS7-based therapeutic strategies to reverse gefitinib resistance in NSCLC. PMID: 29269300
3. Among 8 SNPs in 3 loci that showed at least nominal association (P < 5.00E-02) in the primary cohort, a representative SNP for each loci (rs2157719 for CDKN2B-AS1, rs33912345 for SIX6, and rs9913911 for GAS7) were selected PMID: 29261660
4. These results demonstrate GAS7 as a susceptibility gene for schizophrenia. PMID: 27189492
5. Low GAS7C increases cancer cell motility by promoting N-WASP/FAK/F-actin cytoskeleton dynamics. It also enhances beta-catenin stability via hnRNP U/beta-TrCP complex formation. PMID: 26506240
6. We conclude that lower neuronal Gas7b levels may impact Alzheimer disease progression. PMID: 24151073
7. The results suggest that regulation to maintain an appropriate concentration of hGas7b is required for healthy neurotransmission. PMID: 22496485
8. These findings indicate that Gas7 is involved in motor neuron function associated with muscle strength maintenance. PMID: 22662195
9. Intraocular pressure (IOP)was significantly associated with rs11656696, located in GAS7 at 17p13.1 and with rs7555523, located in TMCO1 at 1q24.1.These data suggest that we have identified two clinically relevant genes involved in IOP regulation. PMID: 22570627
10. regulates the differentiation of mesenchymal stem cells into osteoblasts by enhancing Runx2-dependent gene expression PMID: 21452305
11. Knockdown of Gas7 by shRNA preferentially suppressed the Gas7b protein isoform in human preneuronal cells and to reduce apoptosis induced either by serum starvation or by the antineoplastic agents in human neuroblastoma SH-SY5Y cells. PMID: 20890993
12. This work reports the identification of two human Gas7 cDNA: hGas7-a with 2,427 nucleotides, which encodes 330 amino acids, and hGas7-b with 2,610 nucleotides, which encodes 412 amino acids according to predicted open-reading-frames. PMID: 15948147
13. hGas7b has a role in microtubular maintenance and is possibly implicated in Alzheimer disease PMID: 19801671

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HGNC: 4169

OMIM: 603127

KEGG: hsa:8522

STRING: 9606.ENSP00000407552

UniGene: Hs.462214