GID8 Antibody

Code CSB-PA882124LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA882124LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) GID8 Polyclonal antibody
Uniprot No.
Target Names
GID8
Alternative Names
GID8 antibody; C20orf11 antibody; TWA1Glucose-induced degradation protein 8 homolog antibody; Two hybrid-associated protein 1 with RanBPM antibody; Twa1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Glucose-induced degradation protein 8 homolog protein (1-228AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The GID8 Antibody (Product code: CSB-PA882124LA01HU) is Non-conjugated. For GID8 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA882124LB01HU GID8 Antibody, HRP conjugated ELISA
FITC CSB-PA882124LC01HU GID8 Antibody, FITC conjugated
Biotin CSB-PA882124LD01HU GID8 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Acts as a positive regulator of Wnt signaling pathway by promoting beta-catenin (CTNNB1) nuclear accumulation.
Gene References into Functions
  1. The results identify Twa1 as a previously undescribed regulator of the Wnt pathway for promoting colorectal tumorigenesis by facilitating beta-catenin nuclear retention. PMID: 28829046
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
GID8 family
Tissue Specificity
Up-regulated in colorectal cancer tissues (at protein level).
Database Links

HGNC: 15857

OMIM: 611625

KEGG: hsa:54994

STRING: 9606.ENSP00000266069

UniGene: Hs.353013

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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