HELZ2 Antibody

Code CSB-PA070081
Size US$100
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Product Details

Uniprot No.
Target Names
HELZ2
Alternative Names
ATP-dependent helicase PRIC285 antibody; KIAA1769 antibody; PDIP1 antibody; Peroxisomal proliferator-activated receptor A-interacting complex 285 kDa protein antibody; PPAR-alpha-interacting complex protein 285 antibody; PPAR-gamma DBD-interacting protein 1 antibody; PPAR-gamma DNA-binding domain-interacting protein 1 antibody; PR285_HUMAN antibody; PRIC285 antibody; PRPF8 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human PRIC285.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Helicase that acts as a transcriptional coactivator for a number of nuclear receptors including PPARA, PPARG, THRA, THRB and RXRA.
Gene References into Functions
  1. Thrap3 could play indispensable roles in terminal differentiation of adipocytes by enhancing PPARgamma-mediated gene activation cooperatively with Helz2. PMID: 23525231
  2. Genetic polymorphisms in PRIC285 gene is associated with autoimmune disease. PMID: 22446964
Subcellular Location
Nucleus.
Protein Families
DNA2/NAM7 helicase family
Tissue Specificity
Expressed in various tissues including heart, pancreas, skeletal muscle, colon, spleen, liver, kidney, lung, peripheral blood and placenta.
Database Links

HGNC: 30021

OMIM: 611265

KEGG: hsa:85441

STRING: 9606.ENSP00000417401

UniGene: Hs.517180

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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