HERC4 Antibody

Code CSB-PA010302GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
HERC4
Alternative Names
DKFZP564G092 antibody; HECT and RLD domain containing E3 ubiquitin protein ligase 4 antibody; HECT domain and RCC1 like domain containing protein 4 antibody; HECT domain and RCC1-like domain-containing protein 4 antibody; Hect domain and RLD 4 antibody; HERC 4 antibody; HERC4 antibody; HERC4_HUMAN antibody; KIAA1593 antibody; Probable E3 ubiquitin protein ligase HERC4 antibody; Probable E3 ubiquitin-protein ligase HERC4 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human HERC4
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Probable E3 ubiquitin-protein ligase involved in either protein trafficking or in the distribution of cellular structures. Required for spermatozoon maturation and fertility, and for the removal of the cytoplasmic droplet of the spermatozoon. E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer it to targeted substrates.
Gene References into Functions
  1. HERC4 has an effect on the occurrence and development of hepatoma carcinoma PMID: 28430527
  2. High HERC4 expression is associated with lung cancer. PMID: 25684480
  3. HERC4 ancestor emerged in nematodes and that the family expanded throughout evolution. The mRNA expression pattern of the HERC4 was found to be diverse in selected tissues and cells PMID: 15676274
Subcellular Location
Cytoplasm, cytosol. Note=shows a punctate cytoplasmic distribution.
Tissue Specificity
Expressed in brain and testis and detected in heart and placenta.
Database Links

HGNC: 24521

OMIM: 609248

KEGG: hsa:26091

STRING: 9606.ENSP00000378624

UniGene: Hs.51891

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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