HNRNPH2 Antibody

Code CSB-PA061816
Size US$297
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  • Western blot analysis of extracts from Jurkat cells, 293 cells and K562 cells, using hnRNP H antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) HNRNPH2 Polyclonal antibody
Uniprot No.
Target Names
HNRNPH2
Alternative Names
FTP 3 antibody; FTP-3 antibody; FTP3 antibody; Heterogeneous nuclear ribonucleoprotein H'' antibody; heterogeneous nuclear ribonucleoprotein H2 (H') antibody; Heterogeneous nuclear ribonucleoprotein H2 antibody; HNRH2_HUMAN antibody; hnRNP H'' antibody; hnRNP H2 antibody; hnRNPH' antibody; HNRNPH2 antibody; HNRPH' antibody; HNRPH2 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from internal of Human hnRNP H.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Binds poly(RG).
Gene References into Functions
  1. Results from a study on gene expression variability markers in early-stage human embryos shows that HNRNPH2 is a putative marker for the 3-day, 8-cell embryo stage. PMID: 26288249
  2. identification of six females from independent families with a common neurodevelopmental phenotype including developmental delay, intellectual disability, autism, hypotonia, and seizures, all with de novo predicted deleterious variants in the nuclear localization signal of Heterogeneous Nuclear Ribonucleoprotein H2, encoded by HNRNPH2, a gene located on the X chromosome PMID: 27545675
  3. Data indicate that armadillo repeat protein ARVCF interacts with the splicing factors the splicing factor SRSF1 (SF2/ASF), the RNA helicase p68 (DDX5), and the heterogeneous nuclear ribonucleoprotein hnRNP H2. PMID: 24644279
  4. the relative levels of hnRNP F and H2 in cells, as well as the target sequences in the downstream GRS on pre-mRNA, influence gene expression PMID: 16171461
Involvement in disease
Mental retardation, X-linked, syndromic, Bain type (MRXSB)
Subcellular Location
Nucleus, nucleoplasm.
Tissue Specificity
Expressed ubiquitously.
Database Links

HGNC: 5042

OMIM: 300610

KEGG: hsa:3188

STRING: 9606.ENSP00000361927

UniGene: Hs.432485

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