HOXD11 Antibody

Code CSB-PA975571
Size US$166
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  • Gel: 10+12%SDS-PAGE, Lysate: 30 μg, Lane: Mouse kidney tissue, Primary antibody: CSB-PA975571(HOXD11 Antibody) at dilution 1/1100, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 60 seconds
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Product Details

Uniprot No.
Target Names
HOXD11
Alternative Names
Homeo box 4F antibody; Homeo box D11 antibody; Homeobox D11 antibody; Homeobox protein Hox-4F antibody; Homeobox protein Hox-D11 antibody; Hox-4F antibody; HOX4 antibody; HOX4F antibody; HOXD11 antibody; HXD11_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide of Human HOXD11
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:5000
WB 1:1000-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Gene References into Functions
  1. High expression of HOXD11 is associated with laryngeal squamous cell carcinoma. PMID: 27658780
  2. data show no significant difference in HOXD11, HOXD12 & HOXD13 genotype frequencies between the autism spectrum disorder & healthy controls, but one SNP in promoter region of HOXD11 was observed in only 4 patients with ASD PMID: 19540081
  3. In human embryonic stem cell (hESCs)differentiation, a 1.8kb region between HOXD11 and HOXD12 (D11.12) that is associated with PcG proteins was discovered, it shows alteration in nuclease sensitivity as hESCs differentiate. PMID: 20085705
  4. The HOXD11 gene is fused to the NUP98 gene in acute myeloid leukemia with t(2;11)(q31;p15). PMID: 11782354
  5. Our findings do not support the hypothesis that mutations in the HOXD11 coding regions are involved in the pathogenesis of human non-syndromal congenital renal parenchymal malformations. PMID: 19255789

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Subcellular Location
Nucleus.
Protein Families
Abd-B homeobox family
Database Links

HGNC: 5134

OMIM: 142986

KEGG: hsa:3237

STRING: 9606.ENSP00000249504

UniGene: Hs.421136

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