IDH3G Antibody

Datasheet

Code	CSB-PA952993
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA952993(IDH3G Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA952993(IDH3G Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200) Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Mouse brain tissue, NIH/3T3 cells, Primary antibody: CSB-PA952993(IDH3G Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds
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Product Details
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Target Background

Product Details

Uniprot No.

P51553

Target Names

IDH3G

Alternative Names

H IDHG antibody; IDH gamma antibody; IDH3G antibody; IDH3G_HUMAN antibody; Isocitrate dehydrogenase [NAD] subunit gamma antibody; Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial antibody; Isocitrate dehydrogenase 3 (NAD+) gamma antibody; Isocitric dehydrogenase antibody; Isocitric dehydrogenase subunit gamma antibody; mitochondrial antibody; NAD (H) specific isocitrate dehydrogenase gamma subunit antibody; NAD(+) specific ICDH antibody; NAD(+)-specific ICDH subunit gamma antibody; NAD+ specific ICDH antibody; OTTHUMP00000025984 antibody; OTTHUMP00000025985 antibody; OTTHUMP00000025987 antibody; OTTHUMP00000025988 antibody; OTTHUMP00000214764 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Fusion protein of Human IDH3G

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,WB,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:2000-1:5000
WB	1:500-1:2000
IHC	1:25-1:100

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

Regulatory subunit which plays a role in the allosteric regulation of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.

Gene References into Functions

Aspartate-190 is a determinant of IDH gamma subunit affinity for the manganese (MnII) ion, as well as for nicotinamide-adenine dinucleotide (NAD), but is not directly required for the catalytic reaction. PMID: 17432878

Subcellular Location

Mitochondrion.

Protein Families

Isocitrate and isopropylmalate dehydrogenases family

Database Links

HGNC: 5386

OMIM: 300089

KEGG: hsa:3421

STRING: 9606.ENSP00000217901

UniGene: Hs.410197

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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