LONP2 Antibody

Datasheet

Code	CSB-PA060279
Size	US$119
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Product Details
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Target Background

Product Details

Uniprot No.

Q86WA8

Target Names

LONP2

Alternative Names

Lon peptidase 2, peroxisomal antibody; Lon protease 2 antibody; Lon protease homolog 2 antibody; Lon protease homolog 2 peroxisomal antibody; Lon protease like protein 2 antibody; Lon protease-like protein 2 antibody; LONP antibody; lonp2 antibody; LONP2_HUMAN antibody; LONPL antibody; MGC4840 antibody; peroxisomal antibody; Peroxisomal Lon protease antibody; Peroxisomal Lon protease homolog 2 antibody; Peroxisomal LON protease like antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthesized peptide derived from the C-terminal region of Human LONP2.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB, IHC, ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:100-1:300
ELISA	1:40000

Protocols

Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta-oxidation through degradation of the self-processed forms of TYSND1.

Gene References into Functions

Findings suggest that LONP2 promotes cervical tumorigenesis via oxidative stress. PMID: 29502128
The proteolytic activity of oligomeric Tysnd1 is in turn controlled by self-cleavage of Tysnd1 and degradation of Tysnd1 cleavage products by PsLon. PMID: 22002062
Lon recognizes specific surface determinants or folds, initiates proteolysis at solvent-accessible sites of MPPalpha and StAR, and generates unfolded polypeptides that are then processively degraded PMID: 15870080

Subcellular Location

Peroxisome matrix.

Protein Families

Peptidase S16 family

Tissue Specificity

Widely expressed, with high levels in the liver, kidney and pancreas.

Database Links

HGNC: 20598

OMIM: 617774

KEGG: hsa:83752

STRING: 9606.ENSP00000285737

UniGene: Hs.295923

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Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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