MAGEA11 Antibody

1. SUV39H2 functioned cooperatively with MAGE-A11 to increase androgen-dependent AR transcriptional activity. PMID: 28042025
2. direct interactions of MAGE-A11 with Skp2 and cyclin A regulate the substrate-specificity of Skp2-mediated protein degradation. PMID: 27720894
3. MAGE-A11 and androgen receptor cooperate in the up-regulation of FSTL1 to promote the growth of prostate cancer. PMID: 27976415
4. MAGE-A11 is an independent poor prognostic marker for esophageal squamous cell carcinoma (ESCC) patients. MAGE-A11 regulates various cell functions and directly increases the invasion and proliferation of ESCC cells. PMID: 27362547
5. degradation of MAGE-A11 promoted by the human p14-ARF tumor suppressor contributes to low levels of MAGE-A11 in nontransformed cells PMID: 26330556
6. MAGE-A11, similarly to HER-2 and ER-beta, may be an important diagnostic or prognostic indicator in breast cancer and potentially promotes tumor proliferation. PMID: 23064813
7. MAGEA11 regulation is highly instructive for understanding mechanisms regulating CG antigen genes in human cancer. PMID: 23839233
8. MAGE-A11 is a proto-oncogene whose increased expression in prostate cancer reverses retinoblastoma-related protein p107 from a transcriptional repressor to a transcriptional activator of the androgen receptor and E2F1. PMID: 23853093
9. MAGE-A11 increases AR transcriptional activity by linking androgen receptor dimers. PMID: 23172223
10. the functional defect associated with an AR exon 1 missense mutation. PMID: 22334658
11. Gain in transcriptional activity by primate-specific coevolution of melanoma antigen-A11 and its interaction site in androgen receptor. PMID: 21730049
12. MAGE-11 links NH(2)-terminal domains of AR and p300 to promote transcriptional synergy through a cadre of FXXLF-related interacting motifs PMID: 20448036
13. Results suggest that MAGE-11 functions as a bridging factor to recruit androgen receptor coactivators through a novel FXX(L/I)F motif-F-box interaction paradigm. PMID: 19828458
14. MAGE-11 is a unique AR coregulator that increases AR activity by modulating the AR interdomain interaction. PMID: 15684378
15. The results suggest that MAGE-11 functions as a coregulator that increases AR transcriptional activity during the establishment of uterine receptivity in the human female. PMID: 18048459
16. The time-dependent EGF-induced increase in AR transcriptional activity by MAGE-11 is mediated through AR activation functions 1 and 2 in association with the increased turnover of AR and MAGE-11. PMID: 18212060
17. Knockdown of MAGE-11 by small interfering RNA results in decreased hypoxic induction of HIF-1alpha and its target genes. Inhibition of PHD by MAGE-11, and following activation of HIFs, is a novel tumor-associated HIF regulatory mechanism. PMID: 19147576
18. Increased expression of the AR coregulator MAGE-11 through promoter DNA hypomethylation and cyclic AMP is associated with prostate cancer PMID: 19372581

Show More

Hide All

HGNC: 6798

OMIM: 300344

KEGG: hsa:4110

STRING: 9606.ENSP00000347358

UniGene: Hs.670252