MAP4K5 Antibody

Code CSB-PA013440DSR2HU
Size US$166
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  • Western blot
    All lanes: MAP4K5 antibody at 4.2μg/ml + Mouse brain tissue
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 95 kDa
    Observed band size: 95 kDa

  • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA013440DSR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MAP4K5 Polyclonal antibody
Uniprot No.
Target Names
MAP4K5
Alternative Names
MAP4K5 antibody; Mitogen-activated protein kinase kinase kinase kinase 5 antibody; EC 2.7.11.1 antibody; Kinase homologous to SPS1/STE20 antibody; KHS antibody; MAPK/ERK kinase kinase kinase 5 antibody; MEK kinase kinase 5 antibody; MEKKK 5 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Mitogen-activated protein kinase kinase kinase kinase 5 protein (300-480AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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 Q&A
Q:

Just a quick question in regard to 2 antibodies: What is the major difference between PA013440DSR2 and PA013440DSR1HU?

A:

CSB-PA013440DSR2 and CSB-PA013440DSR1HU are basically the same antibodies, but they were raised in two different rabbits.

Target Background

Function
May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
Gene References into Functions
  1. MAP4K5 expression is decreased or lost in majority of pancreatic ductal adenocarcinoma. PMID: 27023625
  2. TNF signaling leads to oligomerization, ubiquitination, and activation of GCKR and activation of the SAPK pathway in a manner that depends upon TRAF2 polyubiquitination and oligomerization and Ubc13 function PMID: 12591926
  3. The -822G/A polymorphism in the promoter region of the MAP4K5 gene is associated with reduced risk of type 2 diabetes in Han Chinese from Shanghai. PMID: 16699725
Subcellular Location
Cytoplasm.
Protein Families
Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily
Tissue Specificity
Ubiquitously expressed in all tissues examined, with high levels in the ovary, testis and prostate.
Database Links

HGNC: 6867

OMIM: 604923

KEGG: hsa:11183

STRING: 9606.ENSP00000013125

UniGene: Hs.130491

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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