MILR1 Antibody

Code CSB-PA801819LA01HU
Size US$166
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Image
  • Western blot
    All lanes: MILR1 antibody at 14 μg/ml
    Lane 1: Mouse brain tissue
    Lane 2: HepG2 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 39, 28, 29 kDa
    Observed band size: 39, 120 kDa

  • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA801819LA01HU at dilution of 1:100

  • Immunofluorescent analysis of HepG2 cells using CSB-PA801819LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MILR1 Polyclonal antibody
Uniprot No.
Target Names
MILR1
Alternative Names
Allergin-1 antibody; Allergy inhibitory receptor 1 antibody; C17orf60 antibody; Mast cell antigen 32 antibody; Mast cell immunoglobulin-like receptor 1 antibody; MCA-32 antibody; MCA32 antibody; MILR1 antibody; MILR1_HUMAN antibody; Probable mast cell antigen 32 homolog antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Allergin-1 protein (249-343AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The MILR1 Antibody (Product code: CSB-PA801819LA01HU) is Non-conjugated. For MILR1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA801819LB01HU MILR1 Antibody, HRP conjugated ELISA
FITC CSB-PA801819LC01HU MILR1 Antibody, FITC conjugated
Biotin CSB-PA801819LD01HU MILR1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE-mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction.
Gene References into Functions
  1. Data indicate that the rs6504230 polymorphism affects MILR1 (mast cell immunoglobulin-like receptor 1; synonyms, Allergin-1) expression levels, leading to a susceptibility to producing specific IgE antibodies against common allergens. PMID: 25007884
  2. Allergin-1S1, a splicing isoform of Allergin-1, is predominantly expressed on human primary MC in both bronchoalveolar lavage fluid and nasal scratching specimens. Moreover, Allergin-1S1 inhibits IgE-mediated activation from human primary MC in BAL fluid. PMID: 24116093
  3. It is a immunoglobulin-like receptor which regulates the activation of mast cell.(review) PMID: 24552759
Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Tissue Specificity
Expressed in myeloid cells (dendritic cells, macrophages and neutrophils, weak expression on B-cells but not in T-cells or natural killer cells), peripheral blood basophils and mast cells (at protein level).
Database Links

HGNC: 27570

KEGG: hsa:284021

UniGene: Hs.631749

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