MINPP1 Antibody

Datasheet

Code	CSB-PA039513
Size	US$297
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Image	Western blot analysis of extracts from 293 cells, using MINPP1 antibody.
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) MINPP1 Polyclonal antibody

Uniprot No.

Q9UNW1

Target Names

MINPP1

Alternative Names

3 antibody; 4 antibody; 5)-tetrakisphosphate 3-phosphatase antibody; 5)P(4) 3-phosphatase antibody; DKFZp564L2016 antibody; HIPER1 antibody; Inositol (1 antibody; inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase antibody; Ins(1 antibody; ins(1,3,4,5)P(4) 3-phosphatase antibody; MINP1_HUMAN antibody; Minpp1 antibody; MINPP2 antibody; MIPP antibody; Multiple inositol polyphosphate histidine phosphatase, 1 antibody; Multiple inositol polyphosphate phosphatase 1 antibody; multiple inositol polyphosphate phosphatase 2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthesized peptide derived from internal of Human MINPP1.

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Tested Applications

ELISA,WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:3000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification). May play a role in the transition of chondrocytes from proliferation to hypertrophy.

Gene References into Functions

Minpp1 exhibits characteristics of a stress responsive molecule during Endoplasmic reticulum stress-induced apoptosis PMID: 27038811
By RNA knockdown, we identified secreted and lysosome targeted MINPP1 (multiple inositol-polyphosphate phosphatase 1), the mammalian 3-phytase, to be essentially involved both in extracellular and in lysosomal InsP6 dephosphorylation PMID: 23186306

Involvement in disease

Thyroid cancer, non-medullary, 2 (NMTC2)

Subcellular Location

Endoplasmic reticulum lumen.

Protein Families

Histidine acid phosphatase family, MINPP1 subfamily

Tissue Specificity

Widely expressed with highest levels in kidney, liver and placenta.

Database Links

HGNC: 7102

OMIM: 188470

KEGG: hsa:9562

STRING: 9606.ENSP00000361064

UniGene: Hs.121260

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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