MINPP1 Antibody

Code CSB-PA891977EA01HU
Size US$166
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  • Western blot
    All lanes: MINPP1 antibody at 14μg/ml
    Lane 1: Jurkat whole cell lysate
    Lane 2: U251 whole cell lysate
    Lane 3: K562 whole cell lysate
    Lane 4: Hela whole cell lysate
    Lane 5: HepG2 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 56, 35, 32, 34 kDa
    Observed band size: 56 kDa

  • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA891977EA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MINPP1 Polyclonal antibody
Uniprot No.
Target Names
MINPP1
Alternative Names
3 antibody; 4 antibody; 5)-tetrakisphosphate 3-phosphatase antibody; 5)P(4) 3-phosphatase antibody; DKFZp564L2016 antibody; HIPER1 antibody; Inositol (1 antibody; inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase antibody; Ins(1 antibody; ins(1,3,4,5)P(4) 3-phosphatase antibody; MINP1_HUMAN antibody; Minpp1 antibody; MINPP2 antibody; MIPP antibody; Multiple inositol polyphosphate histidine phosphatase, 1 antibody; Multiple inositol polyphosphate phosphatase 1 antibody; multiple inositol polyphosphate phosphatase 2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Multiple inositol polyphosphate phosphatase 1 protein (31-487AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The MINPP1 Antibody (Product code: CSB-PA891977EA01HU) is Non-conjugated. For MINPP1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA891977EB01HU MINPP1 Antibody, HRP conjugated ELISA
FITC CSB-PA891977EC01HU MINPP1 Antibody, FITC conjugated
Biotin CSB-PA891977ED01HU MINPP1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification). May play a role in the transition of chondrocytes from proliferation to hypertrophy.
Gene References into Functions
  1. Minpp1 exhibits characteristics of a stress responsive molecule during Endoplasmic reticulum stress-induced apoptosis PMID: 27038811
  2. By RNA knockdown, we identified secreted and lysosome targeted MINPP1 (multiple inositol-polyphosphate phosphatase 1), the mammalian 3-phytase, to be essentially involved both in extracellular and in lysosomal InsP6 dephosphorylation PMID: 23186306
Involvement in disease
Thyroid cancer, non-medullary, 2 (NMTC2)
Subcellular Location
Endoplasmic reticulum lumen.
Protein Families
Histidine acid phosphatase family, MINPP1 subfamily
Tissue Specificity
Widely expressed with highest levels in kidney, liver and placenta.
Database Links

HGNC: 7102

OMIM: 188470

KEGG: hsa:9562

STRING: 9606.ENSP00000361064

UniGene: Hs.121260

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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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