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MOGS Antibody

Datasheet
Code CSB-PA014713GA01HU
Size $600
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Product Details

Uniprot No.
Q13724
Target Names
MOGS
Alternative Names
EC 3.2.1.106 antibody; glucosidase I antibody; Mannosyl oligosaccharide glucosidase antibody; Mannosyl-oligosaccharide glucosidase antibody; Mogs antibody; MOGS_HUMAN antibody; Processing A glucosidase I antibody; Processing A-glucosidase I antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human MOGS
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor in a highly specific manner.
Gene References into Functions
  1. A shortened immunoglobulin half-life was determined to be the mechanism underlying the hypogammaglobulinemia in congenital disorder of glycosylation type IIb (CDG-IIb). PMID: 24716661
  2. Perturbation of free oligosaccharide trafficking in endoplasmic reticulum glucosidase I-deficient and castanospermine-treated cells. PMID: 11942856
  3. MafF/NFE2 hetrodimers act as weak transcriptional activators, and, in particular, are able to stimulate activity of the GCS1 promoter. PMID: 12490281
  4. identification of sequence motifs responsible for endoplasmic reticulum localization PMID: 12626409
Involvement in disease
Type IIb congenital disorder of glycosylation (CDGIIb)
Subcellular Location
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein Families
Glycosyl hydrolase 63 family
Database Links

HGNC: 24862

OMIM: 601336

KEGG: hsa:7841

STRING: 9606.ENSP00000233616

UniGene: Hs.516119

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Related pathways
Protein processing in endoplasmic reticulum Virus Infection
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