MRPL12 Antibody

Code CSB-PA259631
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA259631(MRPL12 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA259631(MRPL12 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
  • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: 293T cells, Primary antibody: CSB-PA259631(MRPL12 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds
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Product Details

Uniprot No.
Target Names
MRPL12
Alternative Names
39S ribosomal protein L12 antibody; 39S ribosomal protein L12, mitochondrial antibody; 5c5-2 antibody; FLJ60124 antibody; L12mt antibody; MGC8610 antibody; mitochondrial antibody; Mitochondrial ribosomal protein L12 antibody; MRP-L12 antibody; MRP-L31/34 antibody; MRPL12 antibody; MRPL7 antibody; MRPL7/L12 antibody; RM12_HUMAN antibody; RPML12 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Fusion protein of Human MRPL12
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
WB 1:500-1:2000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
As a component of the mitochondrial large ribosomal subunit, it plays a role in mitochondrial translation. Associates with mitochondrial RNA polymerase to activate transcription.
Gene References into Functions
  1. knock-down of MRPL12 by RNA interference results in instability of POLRMT. PMID: 26586915
  2. This mutation resulted in a decreased steady-state level of MRPL12 protein. PMID: 23603806
  3. the MRPL12 interaction with POLRMT is likely part of a novel regulatory mechanism that coordinates mitochondrial transcription with translation PMID: 17337445
Subcellular Location
Mitochondrion.
Protein Families
Bacterial ribosomal protein bL12 family
Database Links

HGNC: 10378

OMIM: 602375

KEGG: hsa:6182

STRING: 9606.ENSP00000333837

UniGene: Hs.109059

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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