MTERF4 Antibody

Code CSB-PA800224LA01HU
Size US$166
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Image
  • Western blot
    All lanes: MTERF4 antibody at 2 μg/ml
    Lane 1: Mouse kidney tissue
    Lane 2: HL60 whole cell lysate
    Lane 3: A549 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 44 kDa
    Observed band size: 44 kDa

  • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA800224LA01HU at dilution of 1:100

  • Immunofluorescent analysis of HepG2 cells using CSB-PA800224LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MTERF4 Polyclonal antibody
Uniprot No.
Target Names
MTERF4
Alternative Names
FLJ16261 antibody; HSPC096 antibody; MGC61716 antibody; MTER2_HUMAN antibody; MTERF domain containing 2 antibody; mTERF domain-containing protein 2 antibody; Mterfd2 antibody; OTTHUMP00000200479 antibody; OTTHUMP00000200519 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Transcription termination factor 4, mitochondrial protein (45-87AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The MTERF4 Antibody (Product code: CSB-PA800224LA01HU) is Non-conjugated. For MTERF4 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA800224LB01HU MTERF4 Antibody, HRP conjugated ELISA
FITC CSB-PA800224LC01HU MTERF4 Antibody, FITC conjugated
Biotin CSB-PA800224LD01HU MTERF4 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Regulator of mitochondrial ribosome biogenesis and translation. Binds to mitochondrial ribosomal RNAs 16S, 12S and 7S and targets NSUN4 RNA methyltransferase to the mitochondrial large ribosomal subunit (39S).
Gene References into Functions
  1. The overexpression of MTERF4 induced a significant increase in the levels of APP protein and secreted Abeta 42 in HEK293-APPswe cells compared with control cells these results suggest that MTERF4 promotes the amyloidogenic processing of APP by inhibiting ADAM10 in HEK293-APPswe cells; therefore, MTERF4 may play an important role in the pathogenesis of Alzheimer's disease. PMID: 27894840
  2. analysis of the 3D crystal structure of the human MTERF4-NSUN4 complex PMID: 22949673
Subcellular Location
Mitochondrion.
Protein Families
MTERF family
Database Links

HGNC: 28785

OMIM: 615393

KEGG: hsa:130916

STRING: 9606.ENSP00000241527

UniGene: Hs.159556

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