MTIF3 Antibody

Code CSB-PA862000ESR2HU
Size US$166
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Image
  • Western blot
    All lanes: MTIF3 antibody at 1.15 μg/ml
    Lane 1: Mouse small intestine tissue
    Lane 2: Rat heart tissue
    Lane 3: Mouse liver tissue
    Lane 4: Hela whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 32 kDa
    Observed band size: 32, 100, 75 kDa

  • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA862000ESR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA862000ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MTIF3 Polyclonal antibody
Uniprot No.
Target Names
MTIF3
Alternative Names
DC38 antibody; IF 3 antibody; IF 3Mt antibody; IF-3(Mt) antibody; IF-3Mt antibody; IF3 antibody; IF3(mt) antibody; IF3M_HUMAN antibody; IF3mt antibody; mitochondrial antibody; Mt antibody; MTIF3 antibody; Translation initiation factor IF 3; mitochondrial precursor antibody; Translation initiation factor IF-3 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Human Translation initiation factor IF-3, mitochondrial protein (1-278AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins.
Gene References into Functions
  1. genetic association studies in cohorts of prediabetic patients at multiple sites: Data suggest that an SNP in MTIF3 (rs1885988) is associated with greater weight loss following lifestyle intervention in overweight/obese subjects with prediabetes. PMID: 26253612
  2. single nucleotide polymorphisms rs4771122 of MTIF3 was the variant most significantly associated with long-term weight loss after surgery. PMID: 26337695
  3. Changes in function or expression of MTIF3 indicates mitochondrial dysfunction and contributes to the risk of Parkinson's disease. PMID: 20887776
  4. the c.798C>T polymorphism of the MTIF3 gene showed allelic association with Parkinson's disease PMID: 17267121
Subcellular Location
Mitochondrion.
Protein Families
IF-3 family
Database Links

HGNC: 29788

KEGG: hsa:219402

STRING: 9606.ENSP00000370508

UniGene: Hs.534582

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