MYL1 Antibody

Code CSB-PA015305GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
MYL1
Alternative Names
A1 catalytic antibody; Alkali myosin light chain 1 antibody; MLC1/MLC3 antibody; MLC1F antibody; MLC1F/MLC3F antibody; MLC3F antibody; Myl1 antibody; MYL1_HUMAN antibody; Myosin light chain 1 skeletal muscle isoform antibody; Myosin light chain 1/3 antibody; Myosin light chain 1/3, skeletal muscle isoform antibody; Myosin light chain A1/A2 antibody; Myosin light chain alkali 1/2 antibody; skeletal muscle isoform antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human MYL1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function.
Gene References into Functions
  1. MLCK and phosphorylated MLC are potential prognostic indicators of leiomyosarcoma. PMID: 28618653
  2. these results provide new insights into the sequences and modifications of myosin light chain isoforms in the human and swine hearts, which will pave the way for a better understanding of their functional roles in cardiac physiology and pathophysiology. PMID: 28427997
  3. These results support the concept of the ATP-induced transient interaction of the essential light chain-1 N-terminus with the motor domain of the myosin head. PMID: 29102634
  4. polymorphism of intron MYL1 was associated with endurance performance, specifically in endurance trainability, but not genetic predisposition, in human adults. PMID: 26473445
  5. This study provides an additional mechanistic link between Angiotensin II and vasoconstriction via SFK-enhanced MLC phosphorylation in smooth muscle cells. PMID: 26011449
  6. MRK is a novel RhoC effector that controls LPA-stimulated cell invasion at least in part by regulating myosin dynamics, ERK and p38 PMID: 23319595
  7. Disturbed myosin binding of mutated hVLC-1 may provide a pathomechanism for the development of hypertrohic cardiomyopathy. PMID: 22131351
  8. In vitro degradation of human recombinant MLC1 by MMP-2 increased after ONOO(-) exposure of MLC1 in a concentration-dependent manner PMID: 20518849
  9. Influenza infection activates a series of signaling pathways that converge to induce myosin light chain (MLC) phosphorylation and remodeling of the actin cytoskeleton. PMID: 21731751

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Database Links

HGNC: 7582

OMIM: 160780

KEGG: hsa:4632

STRING: 9606.ENSP00000307280

UniGene: Hs.187338

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