MYL1 Antibody

Code CSB-PA015305DSR1HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA015305DSR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA015305DSR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MYL1 Polyclonal antibody
Uniprot No.
Target Names
MYL1
Alternative Names
A1 catalytic antibody; Alkali myosin light chain 1 antibody; MLC1/MLC3 antibody; MLC1F antibody; MLC1F/MLC3F antibody; MLC3F antibody; Myl1 antibody; MYL1_HUMAN antibody; Myosin light chain 1 skeletal muscle isoform antibody; Myosin light chain 1/3 antibody; Myosin light chain 1/3, skeletal muscle isoform antibody; Myosin light chain A1/A2 antibody; Myosin light chain alkali 1/2 antibody; skeletal muscle isoform antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Myosin light chain 1/3, skeletal muscle isoform protein (1-150AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function.
Gene References into Functions
  1. MLCK and phosphorylated MLC are potential prognostic indicators of leiomyosarcoma. PMID: 28618653
  2. these results provide new insights into the sequences and modifications of myosin light chain isoforms in the human and swine hearts, which will pave the way for a better understanding of their functional roles in cardiac physiology and pathophysiology. PMID: 28427997
  3. These results support the concept of the ATP-induced transient interaction of the essential light chain-1 N-terminus with the motor domain of the myosin head. PMID: 29102634
  4. polymorphism of intron MYL1 was associated with endurance performance, specifically in endurance trainability, but not genetic predisposition, in human adults. PMID: 26473445
  5. This study provides an additional mechanistic link between Angiotensin II and vasoconstriction via SFK-enhanced MLC phosphorylation in smooth muscle cells. PMID: 26011449
  6. MRK is a novel RhoC effector that controls LPA-stimulated cell invasion at least in part by regulating myosin dynamics, ERK and p38 PMID: 23319595
  7. Disturbed myosin binding of mutated hVLC-1 may provide a pathomechanism for the development of hypertrohic cardiomyopathy. PMID: 22131351
  8. In vitro degradation of human recombinant MLC1 by MMP-2 increased after ONOO(-) exposure of MLC1 in a concentration-dependent manner PMID: 20518849
  9. Influenza infection activates a series of signaling pathways that converge to induce myosin light chain (MLC) phosphorylation and remodeling of the actin cytoskeleton. PMID: 21731751

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Database Links

HGNC: 7582

OMIM: 160780

KEGG: hsa:4632

STRING: 9606.ENSP00000307280

UniGene: Hs.187338

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