NAA25 Antibody

Datasheet

Code	CSB-PA617948ESR1HU
Size	US$166
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Image	Western blot All lanes: NAA25 antibody at 2.12µg/ml Lane 1: Mouse liver tissue Lane 2: Mouse kidney tissue Lane 3: Hela whole cell lysate Lane 4: 293T whole cell lysate Lane 5: A549 whole cell lysate Lane 6: HepG2 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 113, 100 kDa Observed band size: 113, 100 kDa Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA617948ESR1HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA617948ESR1HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) NAA25 Polyclonal antibody

Uniprot No.

Q14CX7

Target Names

NAA25

Alternative Names

C12orf30 antibody; DKFZp667K2112 antibody; FLJ1308 antibody; MDM20 antibody; Mitochondrial distribution and morphology 20 antibody; Mitochondrial distribution and morphology protein 20 antibody; N(alpha)-acetyltransferase 25, NatB auxiliary subunit antibody; N-alpha-acetyltransferase 25, NatB auxiliary subunit antibody; N-terminal acetyltransferase B complex subunit MDM20 antibody; N-terminal acetyltransferase B complex subunit NAA25 antibody; Naa25 antibody; NAA25_HUMAN antibody; NAP1 antibody; NatB complex subunit MDM20 antibody; p120 antibody; TPR repeat-containing protein C12orf30 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human N-alpha-acetyltransferase 25, NatB auxiliary subunit protein (703-972AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Non-catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp-Glu. May play a role in normal cell-cycle progression.

Gene References into Functions

Mdm20 acts as a novel regulator of Rictor, thereby controlling mTORC2 activity, and leading to the activation of PKCalphaS657 and FoxO1. PMID: 26600389
The human NatB complex composed of Naa20 (NAT3) and Naa25 (MDM20) N-terminally acetylates Met-Glu-, Met-Asp-, Met-Asn- and Met-Gln- N-termini, and is important for the structure and function of actomyosin fibers and for proper cellular migration. PMID: 22814378
The C120rf30 gene maps into a region of extensive linkage disequilibrium including several genes that represent functional candidates of type 1 diabetes-susceptibility. PMID: 20089178
Human N-acetyltransferase complexe NatB consists of human N-acetyltransferase 3 and human MDM20. The hMDM20 knockdown decreased the fraction of cells in G(0)/G(1)-phase and increased the fraction of cells in the sub-G(0)/G(1)-phase. PMID: 18570629
There are associations between juvenile idiopathic arthritis and variants in the TNFAIP3, STAT4, and C12orf30 regions that have previously shown associations with other autoimmune diseases, including rheumatoid arthritis and systemic lupus erythematosus. PMID: 19565500
hMdm20 (C12orf30) is an auxiliary subunit of the human NatB N-terminal acetyltransferase complex while hNat3 (NAT5) is the catalytic subunit. This ribosome associated complex acetylates nascent Met-Asp/Glu- polypeptides. PMID: 18570629

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Subcellular Location

Cytoplasm.

Protein Families

MDM20/NAA25 family

Database Links

HGNC: 25783

OMIM: 612755

KEGG: hsa:80018

STRING: 9606.ENSP00000261745

UniGene: Hs.530941

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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