NCKAP5L Antibody

Code CSB-PA012274GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
NCKAP5L
Alternative Names
NCKAP5L antibody; CEP169 antibody; KIAA1602 antibody; FP1193Nck-associated protein 5-like antibody; NCKAP5-like antibody; Centrosomal protein of 169 kDa antibody; Cep169 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human KIAA1602
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Regulates microtubule organization and stabilization. Promotes microtubule growth and bundling formation and stabilizes microtubules by increasing intense acetylation of microtubules. Both tubulin-binding and homodimer formation are required for NCKAP5L-mediated microtubule bundle formation.
Gene References into Functions
  1. Our findings suggest that Cep169 regulates cell growth by interacting with multiple proteins. PMID: 29269292
  2. These data suggest that the dissociation of Cep169 from centrosomes is controlled by Cdk1/Cyclin B during mitosis, and that Cep169 might regulate MT dynamics of mitotic spindle. PMID: 26549230
Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Database Links

HGNC: 29321

OMIM: 615104

KEGG: hsa:57701

STRING: 9606.ENSP00000337998

UniGene: Hs.143067

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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