NME3 Antibody

Datasheet

Code	CSB-PA614400ESR2HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA614400ESR2HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA614400ESR2HU at dilution of 1:100 Immunofluorescent analysis of PC-3 cells using CSB-PA614400ESR2HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) NME3 Polyclonal antibody

Uniprot No.

Q13232

Target Names

NME3

Alternative Names

c371H6.2 antibody; DR-nm23 antibody; Expressed in non metastatic cells 3 antibody; NDK 3 antibody; NDK3 antibody; NDK3_HUMAN antibody; NDP kinase 3 antibody; NDP kinase C antibody; NDPK C antibody; NDPKC antibody; NM23 H3 antibody; nm23-H3 antibody; NM23H3 antibody; NME 3 antibody; NME/NM23 nucleoside diphosphate kinase 3 antibody; Nme3 antibody; Non metastatic cells 3 protein expressed in antibody; Nucleoside diphosphate kinase 3 antibody; Nucleoside diphosphate kinase C antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Nucleoside diphosphate kinase 3 protein (20-169AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis.

Gene References into Functions

Thus Tip60 interacts with RNR and NME3 to provide site-specific synthesis of dNTP for facilitating DNA repair in serum-deprived cells which contain low levels of dNTPs. PMID: 26945015
Down-regulated DR-nm23 expression is associated with invasion and metastasis in colorectal cancer. PMID: 23765094
Among genes correlated to nodal metastatic progression, we verified in vitro that NM23-H3 reduced cell motility. PMID: 17900511

Protein Families

NDK family

Database Links

HGNC: 7851

OMIM: 601817

KEGG: hsa:4832

STRING: 9606.ENSP00000219302

UniGene: Hs.514065

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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