NME3 Antibody

Code CSB-PA614400ESR2HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA614400ESR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA614400ESR2HU at dilution of 1:100

  • Immunofluorescent analysis of PC-3 cells using CSB-PA614400ESR2HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) NME3 Polyclonal antibody
Uniprot No.
Target Names
NME3
Alternative Names
c371H6.2 antibody; DR-nm23 antibody; Expressed in non metastatic cells 3 antibody; NDK 3 antibody; NDK3 antibody; NDK3_HUMAN antibody; NDP kinase 3 antibody; NDP kinase C antibody; NDPK C antibody; NDPKC antibody; NM23 H3 antibody; nm23-H3 antibody; NM23H3 antibody; NME 3 antibody; NME/NM23 nucleoside diphosphate kinase 3 antibody; Nme3 antibody; Non metastatic cells 3 protein expressed in antibody; Nucleoside diphosphate kinase 3 antibody; Nucleoside diphosphate kinase C antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Nucleoside diphosphate kinase 3 protein (20-169AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis.
Gene References into Functions
  1. Thus Tip60 interacts with RNR and NME3 to provide site-specific synthesis of dNTP for facilitating DNA repair in serum-deprived cells which contain low levels of dNTPs. PMID: 26945015
  2. Down-regulated DR-nm23 expression is associated with invasion and metastasis in colorectal cancer. PMID: 23765094
  3. Among genes correlated to nodal metastatic progression, we verified in vitro that NM23-H3 reduced cell motility. PMID: 17900511
Protein Families
NDK family
Database Links

HGNC: 7851

OMIM: 601817

KEGG: hsa:4832

STRING: 9606.ENSP00000219302

UniGene: Hs.514065

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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