NOL8 Antibody

Code CSB-PA030164
Size US$119
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  • Western Blot analysis of 3T3 cells using Nop132 Polyclonal Antibody
  • Western Blot analysis of NIH-3T3 cells using Nop132 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
NOL8
Alternative Names
C9orf34 antibody; NOL8 antibody; NOL8_HUMAN antibody; NOP132 antibody; Nucleolar protein 8 antibody; Nucleolar protein Nop132 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the C-terminal region of Human Nop132.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Plays an essential role in the survival of diffuse-type gastric cancer cells. Acts as a nucleolar anchoring protein for DDX47. May be involved in regulation of gene expression at the post-transcriptional level or in ribosome biogenesis in cancer cells.
Gene References into Functions
  1. nucleolar protein 132(Nop132) is associated with the GTP form, but not the GDP form, of ras-related GTP binding protein RRAG A, suggesting that RRAG A might regulate Nop132 function PMID: 14660641
Subcellular Location
Nucleus, nucleolus. Note=Localizes in the nucleolar-organizing region during ribosome biogenesis.
Tissue Specificity
Expressed in various diffuse-type gastric cancers. Detected at lower levels in skeletal muscle.
Database Links

HGNC: 23387

OMIM: 611534

KEGG: hsa:55035

STRING: 9606.ENSP00000401177

UniGene: Hs.442199

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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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