NOL9 Antibody

Code CSB-PA150875
Size US$166
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Image
  • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Hela cells, Primary antibody: CSB-PA150875(NOL9 Antibody) at dilution 1/1250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds
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Product Details

Uniprot No.
Target Names
NOL9
Alternative Names
NOL9Polynucleotide 5'-hydroxyl-kinase NOL9 antibody; EC 2.7.1.- antibody; Nucleolar protein 9 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Fusion protein of Human NOL9
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
WB 1:500-1:2000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Polynucleotide 5'-kinase involved in rRNA processing. The kinase activity is required for the processing of the 32S precursor into 5.8S and 28S rRNAs, more specifically for the generation of the major 5.8S(S) form. In vitro, has both DNA and RNA 5'-kinase activities. Probably binds RNA.
Gene References into Functions
  1. we present the nol9sa1022/sa1022 mutant, a novel zebrafish ribosomopathy model, which recapitulates key human disease characteristics. PMID: 26624285
  2. The polynucleotide kinase activity of Nol9 is required for efficient generation of the 5.8S and 28S ribosomal RNAs from the 32S precursor. PMID: 21063389
Subcellular Location
Nucleus. Nucleus, nucleolus. Note=Colocalizes with pre-60S rRNP particles.
Protein Families
Clp1 family, NOL9/GRC3 subfamily
Database Links

HGNC: 26265

KEGG: hsa:79707

STRING: 9606.ENSP00000366934

UniGene: Hs.59425

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