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OSGEP Antibody

Datasheet
Code CSB-PA017256GA01HU
Size $600
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Product Details

Uniprot No.
Q9NPF4
Target Names
OSGEP
Alternative Names
FLJ20411 antibody; GCPL-1 antibody; GCPL1 antibody; hOSGEP antibody; KAE1 antibody; O sialoglycoprotein endopeptidase antibody; OSGEP antibody; OSGEP_HUMAN antibody; OSGEP1 antibody; Pasteurella haemolytica metalloprotease homolog with glycoprotein substrates/gpc-like protein 1 antibody; Probable O sialoglycoprotein endopeptidase antibody; Probable tRNA threonylcarbamoyladenosine biosynthesis protein osgep antibody; PRSMG1 antibody; Prsmg1/Gcpl1 antibody; t(6)A37 threonylcarbamoyladenosine biosynthesis protein osgep antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human OSGEP
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC,IF
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Related Products

OSGEP antibodies

OSGEP Proteins

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Target Background

Function
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
Gene References into Functions
  1. Mutation in KAE1 interfering with global protein production was identified in two patients with developmental delay, renal defect and hypomagnesemia. PMID: 28272532
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
KAE1 / TsaD family
Tissue Specificity
Widely expressed at low level. Expressed in heart, placenta, liver, kidney, lung, brain, skeletal muscle and pancreas.
Database Links

HGNC: 18028

OMIM: 610107

KEGG: hsa:55644

STRING: 9606.ENSP00000206542

UniGene: Hs.525196

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