PABPC5 Antibody

Code CSB-PA007315
Size US$100
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Product Details

Uniprot No.
Target Names
PABPC5
Alternative Names
PABPC5 antibody; PABP5 antibody; Polyadenylate-binding protein 5 antibody; PABP-5 antibody; Poly(A)-binding protein 5 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human PABP5.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo.
Gene References into Functions
  1. although function of PABPN1 may be compensated by nuclear translocation of PABP4 and perhaps by increase the cytoplasmic abundance of PABP5, these were not sufficient to prevent apoptosis of cells. PABPN1 may have an anti apoptotic role in mammalian cells PMID: 23300856
Subcellular Location
Cytoplasm.; [Isoform 2]: Mitochondrion matrix. Note=Co-fractionates with mtDNA and co-immunoprecipitates with the mitochondrial poly(A) polymerase.
Tissue Specificity
Expressed in fetal brain and in a range of adult tissues.
Database Links

HGNC: 13629

OMIM: 300407

KEGG: hsa:140886

STRING: 9606.ENSP00000308012

UniGene: Hs.246590

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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