PARP6 Antibody

Code CSB-PA017470GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
PARP6
Alternative Names
1700119G14Rik antibody; 2310028P13Rik antibody; 3110038K10Rik antibody; ADP-ribosyltransferase diphtheria toxin-like 17 antibody; ARTD17 antibody; C030013N01Rik antibody; MGC131971 antibody; PARP 6 antibody; PARP 6 B1 antibody; PARP 6 C antibody; PARP-6 antibody; PARP6 antibody; PARP6_HUMAN antibody; pART17 antibody; poly (ADP ribose) polymerase family; member 6 antibody; Poly [ADP ribose] polymerase 6 antibody; Poly [ADP-ribose] polymerase 6 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human PARP6
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins.
Gene References into Functions
  1. Results showed that both PARP6 and survivin exhibited higher expression in colorectal adenocarcinoma tissues and cell lines. knockdown of either PARP6 or survivin promotes cell apoptosis and inhibits the cell invasion of colorectal adenocarcinoma cells suggesting a significant correlation between theses 2 proteins. PMID: 28260087
  2. PARP6 acts as a tumor suppressor via downregulating Survivin expression in CRC. PARP6 can be a novel diagnostic and therapeutic target together with Survivin for CRC. PMID: 26934315
  3. PARP6, a mono(ADP-ribosyl) transferase and a negative regulator of cell proliferation, is involved in colorectal cancer development, PARP6-positive colorectal cancer had a good prognosis. PMID: 23042038
Database Links

HGNC: 26921

KEGG: hsa:56965

STRING: 9606.ENSP00000287196

UniGene: Hs.270244

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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